FITC标记的线粒体核糖体蛋白S4抗体
产品名称： FITC标记的线粒体核糖体蛋白S4抗体
英文名称： Anti-MRPS4/FITC
产品编号： HZ-9624R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-MRPS4/FITC Conjugated antibody
FITC标记的线粒体核糖体蛋白S4抗体
| 产品编号 | bs-9624R-FITC |
| 英文名称 | Anti-MRPS4/FITC |
| 中文名称 | FITC标记的线粒体核糖体蛋白S4抗体 |
| 别 名 | BRMS2; C15orf12; Chromosome 15 open reading frame 12; imp3; IMP3_HUMAN; Mitochondrial ribosomal protein S4; MRPS4; U3 small nucleolar ribonucleoprotein protein imp3; U3 snoRNP protein 3 homolog; U3 snoRNP protein imp3. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 心血管 细胞生物 免疫学 发育生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Cow, Horse, Rabbit, Guinea Pig, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 22kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human U3 small nucleolar ribonucleoprotein protein IMP3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Imp3, is a 184 amino acid protein that contains one S4 RNA-binding domain and is the mammalian homolog of the yeast Imp3 protein. Localized to the nucleus, Imp3 exists as a component of a heterotrimeric complex consisting of MPP10, Imp3 and Imp4 and, in this complex, plays a key role in early cleavage events during pre-18S ribosomal processing. The gene encoding Imp3 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes. Function: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. Subunit: Component of a heterotrimeric complex containing IMP3, IMP4 and MPHOSPH10. Interacts with MPHOSPH10. Subcellular Location: Nucleus, nucleolus. Similarity: Belongs to the ribosomal protein S4P family. Contains 1 S4 RNA-binding domain. Database links: Entrez Gene: 55272 Human Entrez Gene: 102462 Mouse Entrez Gene: 315697 Rat Omim: 612980 Human SwissProt: Q9NV31 Human SwissProt: Q921Y2 Mouse Unigene: 513043 Human Unigene: 12864 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
IMP3是含有一个S4 RNA结合结构域的184个氨基酸蛋白，是酵母IMP3蛋白的哺乳动物同源物。IMP3存在于细胞核中，作为MMP10、IMP3和IMP4组成的异三聚物的一个组分存在，在该复合物中，在前18S核糖体处理中，在早期裂解事件中起着关键作用。编码IMP3的基因映射到人类15号染色体，该基因包含700个以上的基因，并包含人类基因组的近3%。安吉曼综合征、Prader Willi综合征、Tay-Sachs病和马凡综合征均与15号染色体定位基因的缺陷有关。