FITC标记的胞吐分泌蛋白Sec8抗体
产品名称： FITC标记的胞吐分泌蛋白Sec8抗体
英文名称： Anti-Sec8/FITC
产品编号： HZ-11368R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Sec8/FITC Conjugated antibody
FITC标记的胞吐分泌蛋白Sec8抗体
| 产品编号 | bs-11368R-FITC |
| 英文名称 | Anti-Sec8/FITC |
| 中文名称 | FITC标记的胞吐分泌蛋白Sec8抗体 |
| 别 名 | dSec8; EXOC 4; Exoc4; EXOC4_HUMAN; Exocyst complex component 4; Exocyst complex component Sec8; KIAA1699; MGC27170; REC 8; REC8; rSec 8; Sec 8; Sec 8p; Sec8; SEC8 like 1; SEC8 protein; Sec8L1; Sec8p. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Cow, Horse, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 110kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Sec8 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Function: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Subunit: The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8. Interacts with BIRC6/bruce. Interacts with MYRIP. Similarity: Belongs to the SEC8 family. Database links: Entrez Gene: 60412 Human Entrez Gene: 20336 Mouse Entrez Gene: 116654 Rat Omim: 608185 Human SwissProt: Q96A65 Human SwissProt: O35382 Mouse SwissProt: Q62824 Rat Unigene: 321273 Human Unigene: 265512 Mouse Unigene: 51841 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
由该基因编码的蛋白质是胞外复合物的一个组成部分，是一种多蛋白复合物，其主要靶向胞外囊泡到质膜上的特定对接位点。虽然在酵母中表现最好，但胞外复合物的组成蛋白和功能在高等真核生物中被高度保守。至少有八个成分的胞外复合物，包括这种蛋白质，发现与肌动蛋白细胞骨架重塑和囊泡运输机制。该复合物对于上皮细胞表面极性的生物发生也是必不可少的。编码不同的异构体的交替转录剪接变异体已被表征。