重组人转铁蛋白受体蛋白
| 英文名称 | Recombinant human Transferrin R / CD71 protein, N-His |
| 中文名称 | 重组人转铁蛋白受体蛋白 |
| 别 名 | Transferrin receptor protein 1; TFRC; CD 71; CD71; CD71 antigen; p90; T9; TFR 1; TFR; TFR1; TR; sTfR; Transferrin receptor (p90 CD71); Transferrin Receptor Protein 1; OTTHUMP00000208523; OTTHUMP00000208524; OTTHUMP00000208525; TRFR; TFR1_HUMAN; Recombinant human Transferrin R / CD71 protein, N-His |
| 理论分子量 | 73.8kDa |
| 检测分子量 | 70 kDa |
| 性 状 | Liquid |
| 浓 度 | ＞0.5 mg/ml |
| 物 种 | Human |
| 序 列 | 101-760/760 |
| 纯 度 | >90% as determined by SDS-PAGE |
| 纯化方法 | AC |
| 内毒素 | Not analyzed |
| 表达系统 | E.coli |
| 活性 | Not tested |
| 标签 | N-His |
| 缓 冲 液 | 20 mM Tris-HCl (pH=8.0) |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | Cellular uptake of iron occurs via receptor mediated endocytosis of ligand occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Useful in studies of dividing haematopoietic and tumour cell populations, and metabolic activity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C terminal binding site. The antigen is present on most dividing cells, including normally cycling in vivo hematopoietic progenitor cells, mitogenically stimulated cells in vitro, some primary tumor cells and most proliferating cells in vitro |
| 产品图片 |
 The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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